The Brigalow Belt South Bioregion is in northern NSW and southern Qld, from the south of Dubbo in central-western NSW to the mid-Qld coast.The bioregion occupies a total of 27,196,933 hectares. Of these, 5,333,469 hectares (19.61 per cent) fall within NSW, occupying 6.7 per cent of the state.
Nandewar and North Coast bioregions in the east, the Sydney Basin and South Western Slopes bioregions to the south and the Darling Riverine Plains Bioregion on its western border.
Baradine, Binnaway, Coonabarabran, Dubbo, Gunnedah, Merriwa, Moree and Narrabri.
MacIntyre, Gwydir, Namoi, Castlereagh, Goulburn, Talbragar and Macquarie Rivers, which catchments form an integral part of the Murray-Darling River System. The Liverpool Range in the southeastern corner of the bioregion feeds the headwaters of the Hunter and Namoi Rivers.